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Myeloprotective Effect of Combined Application of Ukrainian-Made Recombinant Granulocyte Colony Stimulating Factor (R-GCSF) and С2 Enterosorbent in Rats with Malignant Guerin Carcinoma

TitleMyeloprotective Effect of Combined Application of Ukrainian-Made Recombinant Granulocyte Colony Stimulating Factor (R-GCSF) and С2 Enterosorbent in Rats with Malignant Guerin Carcinoma
Publication TypeJournal Article
Year of Publication2015
AuthorsTodor, IM, Lukianova, NYu., Rodionova, NK, Shevchuk, OO, Nikolaev, VG, Chekhun, VF
Short TitleSci. innov.
DOI10.15407/scine11.02.043
Volume11
Issue2
SectionResearch and Engineering Innovative Projects of the National Academy of Sciences of Ukraine
Pagination43-48
LanguageEnglish
Abstract

The study is aimed at analyzing myeloprotective effect of new enterosorbents used separately and in combination with two recombinant granulocyte colony stimulating factors: Neupogen (Switzerland) and r-GCSF (Ukraine). The Ukrainian-made r-GCSF has been proved to be as therapeutically efficient as Neupogen (Switzerland); its combined use with C2 enterosorbent significantly increases myeloprotective effect of both GCSF versions.
Keywordsenterosorption, granulocyte colony stimulating factor, myelosupression, tumor
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